Podcast The Hemp Revolution

What Is Nanotechnology and Why Is It Essential for the Cannabis and Hemp Industry with Dr. Alexey Peshkovsky

On average, an adult human body is composed of up to 60% of water, which is why water-soluble substances can enter the bloodstream in a short period of time.

On the other hand, the natural form of plant extracts is oil or fat, and we all know that oil and water simply don’t mix together. Therefore, cannabinoids, in its original form, are not water-soluble. Now, the question is, how can we get around this?

Dr. Alexey Peshkovsky, the Co-founder, President, and Chief Science Officer of Industrial Sonomechanics, has the answer. He is responsible for setting the strategic direction of the company and overseeing instrumentation and applications development.

Dr. Peshkovsky received his B.A. in Chemistry from the University of Pennsylvania and Ph.D. in Physical Chemistry from Columbia University.

His professional experience includes over 25 years as a researcher, entrepreneur, product developer, and scientific director, mainly focusing on instrumentation design, and process development for the medical physics, pharmaceutical and cannabis industries.

Join us in this episode as he talks about the different ways of delivering cannabis to the bloodstream, what nanotechnology is, and why it makes oil-based products like cannabis or hemp more bioavailable for us. He also shares about the turnkey solution that they’ve developed. It’s absolutely brilliant. So, buckle up and stay tuned.


Sufficient education, self-education that allows one to be compliant with what is likely to come as far as regulations go is extremely important, and it’s good to start now because it takes a while to figure it out and to get this right and I think it takes about the same amount of time as it will take the agencies to start regulating. – Dr. Alexey Peshkovsky


Download The Episode Companion For This Episode

Some Topics We Discussed Include

3:34 – A little bit about Dr. Alexey Peshkovsky history
11:38 – Dr. Peshkovsky discusses what nanotechnology is, how, and why it is essential for the cannabis and hemp industries.
23:21 – How serious big pharmacies are about integrating into the cannabis space
32:03 – Some of the challenges he encountered when he started to serve the cannabis industry
42:05 – Key pieces of advice for people considering getting into the space
47:23 – Where to them

People Mentioned / Resources

Connect with Dr. Alexey Peshkovsky

Connect with Sonia Gomez

Transcript

Sonia Gomez: What’s up, guys? Welcome back to The Hemp Revolution Podcast. I’m your host Sonia Gomez. And we are telling yet another incredible story from an entrepreneur who has truly done some pretty unique things in this space. As you know, it is our mission here to empower you with the truth about cannabis and hemp, so that you can make educated decisions about how you want to care for yourself, the people that you love, conditions that you may be suffering from, or otherwise care for this incredible gift of life that we get to enjoy. 

If you’re someone looking for products that you can depend on to deliver the results you’re looking for, check us out at medical.secrets.com. If you’re a budding entrepreneur or an established business owner looking for those unique tips and tricks, resources or relationships that can move the needle and help you break through the glass ceilings and brick walls of this industry, go ahead and check us out at theemeraldcircle.com, we are happy to help. 

Our guests today– Guys, we are diving into the science of this whole thing. Our guest, Dr. Alexey Peshkovsky, is the co-founder, President, and Chief Scientific Officer of Industrial Sonomechanics. He is responsible for setting the strategic direction of the company and overseeing instrumentation and applications development. 

Dr. Peshkovsky received his BA in chemistry from the University of Pennsylvania and Ph.D. in physical chemistry from Columbia University. I mean, you guys, we are going to be getting our socks rocked today with some science around here. 

His professional experience includes over 25 years as a researcher, entrepreneur, product developer, and scientific director, mainly focusing on instrumentation design, and process development for the medical physics, pharmaceutical and cannabis industries. Our guest is also the author of over 40 scientific papers, utility patents, conferences, presentations, and books. Put your hands together and help me welcome our good friend, Dr. Alexey Peshkovsky. Hi, Alexi. How are you? 

Dr. Alexey Peshkovsky: Hi, how are you? 

Sonia Gomez: I’m doing good. Thank you. I’m super happy to have you on. Are you doing a lot of podcasts or media? Usually, someone with your credentials who are hiding behind the scenes being the puppeteer rather than the puppet.

Dr. Alexey Peshkovsky: Yes. I think I’m still a puppet? I’m doing more– Well, I guess I’m doing my fair share. I like doing them, though.

Sonia Gomez: Yes, I mean, you’ve published over 40 different presentations, papers, utility patents, I can’t wait to dive into all of the different things that you have done. Before we get too deep, why don’t you just take a moment and introduce yourself? Share a little bit about who you are, what your background is, and how you ended up in the cannabis boom? 

A Little Bit About Dr. Alexey Peshkovsky History

Dr. Alexey Peshkovsky: Sure. So I’m originally a chemist. I’m trained as a chemist, and then I worked for about 15 years in magnetic resonance, mainly in MRI, magnetic resonance imaging, designing MRI equipment for research hospitals and research centers that want to do things like functional MRI where you can do a simple task or a complicated task. And we can see your brain light up in certain ways [00:04:12 inuadible] what you’re doing. 

I mean, it sounds a little bit more advanced than it actually is. It’s full of unresolved issues and questions and whatnot. Look, it’s a very cool heel. But then I had a little company in that, which was very interesting but it’s a pretty small market because there is not too many research, like hospitals and universities that work in this kind of thing so quickly saturate the market. 

Then I worked in explosive detection that was after 911 a little bit. And after that, I went into ultrasound technology because my father was essentially always like he was an ultrasound physicist. He developed the concept of what we call The Barbell Horn, which long story short, gives you the ability to take a small scale lab experiment of some sort, any type of research and development that you might be doing with ultrasound, and we can talk about what else some could be used for him. 

Anyway, the problem in the field has always been that you could do all these wonderful things on a large scale and publish papers about it. But as soon as you scale up, you would lose the intensity of ultrasound, and therefore the results would not be the same. So it was always believed to be basically a non-scalable technique. And with the Barbell Horn technology, as we call it, there is a way to scale up without changing the results. Basically, with me, this technology is scalable. Well, my father kind of invented the concept of doing that. He convinced me to join him in creating this company, so we founded the company together. 

I’m trained as a chemist but also worked in electrical engineering and instrumentation development so we can understand each other well enough. He was a hardware guy, and I was kind of interface between hardware and applications, then the applications pretty quickly became mainly in nano things. So option on the good for many different things. And we’re not talking about the detection office, not the medical ultrasound that lets you see inside your body or see babies and things like that, but it’s an ultrasound that’s used in industry to do something, to change a material, right? So one of the most interesting changes was making nanoparticles, and that’s useful in a variety of industries, most importantly, in the pharmaceutical industry, because it turns out that through nanoparticles, you can improve drug delivery. 

So, as more of a chemist, I was at the interface between the hardware and the applications. And so we started developing the technology not in general, but with this particular area of application in mind. And pretty quickly, the focus became the pharmaceutical industry, because they have a pretty acute need to develop methods to deliver drugs into the bloodstream. It’s challenging because of drugs, the most bioactive substances are non-water compatible. They don’t dissolve in water. They’re hydrophobic. And it’s challenging to deliver them into a predominantly water-based human body in the bloodstream, which is more water than anything else, right? 

It turns out that when you make them into nanodroplets suspended in the water, they behave as if they were water-soluble. So if you take an oil that doesn’t want to be absorbed by the body very efficiently and make nanoparticles suspension [00:08:19 unintelligible] to behave more like let’s say alcohol, like an alcoholic beverage, which is water-soluble, and so it acts quickly unlike all these oily preparations, and then we worked with the pharma industry for over ten years, I would say. It took a while to develop this properly and to create the formulations to accompany the technology. 

And then this cannabis industry just exploded. With the same desire to deliver a non-water-compatible bioactive substance, which is CBD, THC, or whatever cannabinoids you might want to deliver into the bloodstream. Right? And luckily, we were already kind of done with developing the technology for it. So I guess we just got lucky and we were ready for it. And we’re very quickly started seeing more and more demand in this area and gradually started getting away from the general pharmaceutical applications and more into cannabis. And now I would say it’s 85% of what we do. I guess that’s the story.

Sonia Gomez: So you develop this incredible technology that’s now pretty much required by any brands if they want to be having an advanced technology to deliver their products in. I mean, there’s a lot of companies who are popping up every single day. Dozens and dozens of brands are coming up every day. Most are me-too products. They find a manufacturer that they’re white labeling through and very few have a unique delivery system, or an even fewer has their desired results, I think the consumer is really still challenging to find brands that they can align with that will actually deliver the results that are promised. 

I was speaking with another friend of mine who is also a chemical engineer and very, very educated when it comes to nano, micelle, all of these different breakdowns on a molecular level of this plant and its matters and how to make it most effective delivery system for our human bodies. And he was explaining that it was extremely difficult to– he was saying that it’s difficult to explain nanoparticles for the delivery system of CBD because it only takes such a small amount of oil or milligrams for it to give the desired result for the human body. You don’t have to use really high milligrams like 3000, 4000, or 5000-milligram tincture bottles. 

So I would love to hear you since you’re the creator, I would love to hear you try and explain in the Homer Simpson language, why nanoparticles are important to incorporate with, I think you did a really good job with the alcoholic beverage analogy. But for the people who don’t really understand what nanotech is or why it makes a CBD product or an oil-based product like cannabis or hemp more bioavailable for us Can you just explain in the first-grade level language, how and why this is important advancements for science and for the cannabis and hemp industry in our products.

What Is Nanotechnology and How, and Why It Is Essential for the Cannabis and Hemp Industries?

Dr. Alexey Peshkovsky: I can try. So to be fair, there are many different ways of delivering cannabis to the bloodstream. It doesn’t have to be digested. Obviously, everybody knows that you can smoke it. And then the availability supposedly is higher, although it’s questionable because your exhale and what you exhale contains a lot of stuff that you could have delivered into the bloodstream if you didn’t have to exhale it. The viability of that depends on how you smoke it, but it’s generally believed to be significantly higher than an edible, right? Same for vaping and seems safer, although sometimes [00:12:24 inaudible]

No, no, it’s not so safe, but edibles are very attractive in that there are discreet and very convenient. You don’t have to smoke anything or vape anything, and you can just consume it easily, but the issue is the bioavailability. So on the plus side, if you deliver things through your stomach and small intestine, or digest it in, on the plus side, you have the advantage of using the system that your body actually intends to use when it brings substances into the bloodstream. The lungs could be tricked into delivering things into the bloodstream as well as we all know, but they’re not really meant for that; they’re meant for oxygen. They’re not meant for other bioactive, right? If you can go [00:13:39 unintelligible], I guess maybe you can. 

So you can trick the lungs into doing this for you, but it’s connected to all kinds of problems because there are no safety mechanisms and digestively, there are plenty of safety mechanisms of the body knows to use because when you eat things there’s a wide variety of things that you could eat and the body knows to deal with it properly, right? So that’s on the plus side. On the minus side, since cannabis oils are not compatible with water, the bioavailability is low. 

So, the question is, why nanotechnology– Why does nanotechnology improve the situation? So, I guess in one phrase, you could say that consumption of beverage with a nanoparticle suspension of cannabis oils is similar to vaping through your small intestine. The mechanism is somewhat similar, although it uses your small investments. So you get all the plus sides of the digestive delivery and the safety control. But you get the enhanced bioavailability. Now, why? If you consume a plant oil—olive oil or whatever oil you might be consuming for animal fat. Let’s say you ate a piece of meat, right? So how does the fat gets absorbed? And we all know that it does get absorbed, right?

What happens is it, of course, goes into your stomach. In the stomach, it does not get absorbed, although I hear a lot of people saying that things get absorbed in your stomach better or worse. That’s incorrect. Oils do not get absorbed in the stomach. They sit on the stomach and wait their turn to empty into the small intestine. Then they empty into the small intestine. In the stomach, they also get slightly emulsified. Meaning you have this blob of oil like a big drop or whatever. Some quantity of oil it’s all together. It’s not distributed below the gastric fluid because it’s not water compatible. 

But there are some surface-active molecules [00:16:07 unintelligible] and things like that. So they make like a very crude milky type emulsion it’s like very fatty milk. And that gets emptied into the small intestine where a lot more of those entities come and also enzymes come, and they clip the head of all the triglycerides—triglyceride is the animal fats and oils, fine oils. They are basically like a fork with three teeth. They have a head-on three long chains of fatty acids hanging off of that. So the enzymes clip the head off, that’s glycerin, and that’s just gonna follow its own pathway. We’re not interested in that anymore. 

Now, you’ve created these three fatty acids. They, combined with some bile salts and phospholipids that are locally available, and form into what’s called mixed micelles. Now mixed micelles are nanoparticles of approximately 20 nanometers, give or take depending on what they contain inside, in size. And they are covered with naturally occurring surfactants. So, there are nanoparticle suspensions that are work compatible. They’re not technically water-soluble, a solution is something else. But for all intents and purposes, they’re compatible with water in the sense that they can travel through it and be homogeneously dispersed in it, which is the only thing that you’re actually looking for if you’re maximizing delivery. 

So, these [00:17:53 unintelligible] nanoparticles are dispersed in the gastric fluids. And because they can travel through water, they can get through something called unstirred aqueous, unstirred water layer that follows the aligning of your small intestine. They can get to the other side of that and get to the absorption and desolate cells that are actually responsible for absorbing things. That’s all you want from them. You want them to shuttle the free fatty acids so that you’re concise. This is all before the bloodstream. Before anything, it’s still inside your small intestines. 

Now, if you have any oils that are not digestible and by digestible, I mean they are not triglycerides, you can’t clip their head off and make free fatty acids out of them. If you have any other oils, or whatever those might be vitamins, for example, or cannabis oils, they will not naturally find their way to the inside of those mixed micelles. Now you’ve created something called [00:18:58 unintelligible] micelles. They’re a slightly bigger still nano particles that are about the same size. They travel to where you want them to travel, which is the absorption sites, and then they can be absorbed. 

It’s important to point out that before they get absorbed, they should fall apart, so they don’t go in entirely. Then, they go into the absorbed [00:19:21 unintelligible]; a couple of things can happen to them. They can go into the lymphatic system, or they can go into the bloodstream and on the liver. We can talk more about that if you’d like. But this is sort of beside the point right now. Now, the reason that an edible takes such a long time to kick in to start acting is because it takes an hour for these entities to form to even begin to form in sufficient concentrations for them to get anywhere, okay? That’s why for an hour, you feel nothing for at least an hour, right? Now put–

Sonia Gomez: [00:19:54 inaudible] 

Dr. Alexey Peshkovsky: Right, and then slowly, it starts to build. By then, you probably think you didn’t take it off and then take another of those, and now maybe you’re feeling a little bit better, but then three hours later, both doses are gonna hit you, and now you’re orbiting Saturn.

That is the reason for such a slow onset time for physician delayed onset, right. And because these processes are in competition with just natural progression through the small intestine and out, you’re eliminating this stuff from your body as you’re trying to absorb it. So if it’s slow, that also means that it’s gonna basically just not be available anymore, and then be out of your system before you could take advantage of it. That’s why an edible requires such a high dose and take such a long time. It’s about 6% bioavailable, this general consensus unless it’s on a full stomach, which actually helps because you can make more mixed micelles from that from faster equal administer with cannabinoids and people know in general that if you put it on the full stomach, it hits you harder. And that’s because you have this transportation mechanism and then it goes up to maybe 20% or so, but it’s still pretty well. 

Now the reason nano emulsions and this is the punchline, the reason nanoemulsion are fast and very efficient in delivering this is because nanoemulsion droplets are essentially mimicking mixed micelles. You don’t have to make them. If you consume a beverage with properly prepared nanoemulsions, very small droplets. And by small I mean, preferably well below 50 nanometers. So around the size of mix micelles to 30 nanometers is okay for so right. That’s what you would be forming for an edible very slowly, but you’re consuming it already kind of pre-digested outside of your body if you will. So it’s immediately bioavailable. It’s very fast. And it’s very complete because there is no elimination or competition. Right?

Sonia Gomez: Yeah, that–

Dr. Alexey Peshkovsky: [00:22:18 inaudible] It’s kind of like vaping through your small intestine because when you vape, you create small, tiny suspended droplets in the air that very efficiently go through your lungs into the bloodstream. This is very small droplets suspended in water that very efficiently go into your bloodstream or limb, lymphatic fluid through your small investment.

Sonia Gomez: So for folks who are listening in and for those of you especially who have brands and businesses, and you’ve been looking at the traditional delivery systems, it’s important to start to think about how we can gain fast, effective results through our products and breaking down the molecule so that they are in fact absorbable through the human bloodstream is something to definitely pay attention to because it’s a known fact that big pharma and big business are on their way into this industry, especially as we’re looking at global or how should I say national legalization? 

Alexey, I’m interested to hear from your perspective, since you’re working with both pharmaceutical and cannabis, how soon or how serious should I say is big pharma, about integrating into the cannabis and CBD space? And are you involved with trouble– You probably can’t tell me, but I’m asking anyway. Are you involved with starting to create solutions or formulations that would allow them to bridge into our space?

How Serious Big Pharmacies Are About Integrating Into the Cannabis Space

Dr. Alexey Peshkovsky: Sure. I’ll start, I guess from the last question is, we’re not specifically involved with pharma on this, there is no need for that. There’s no need to be specific. We have the formulation that we offer. We call it a nano stabilizer. It’s the entire formulation that’s necessary to make nanoparticles. All you have to use is your original raw material—isolate, extract, full-spectrum oil, whatever you have plus ultrasonic system, and anybody can do it, including pharma. We don’t discriminate who our customers are, but they are taking their time, then it may have something to do with the legal situation. Most likely, it does. It also has probably to do with the fact that they have very, very strict control over what they do for good reasons.

It’s hard for them to work with natural materials. They prefer to synthesize. Things like Marinol and synthetic THC that they make because then we know exactly what they have, and they can categorize it because it’s one thing, it’s very hard to characterize things that are not one thing, right? And you have to do a lot of that if you’re a pharma company, so it’s really hard for them to work with national express. I would expect them if they bark or enter to start with probably isolates. But I don’t feel a lot of activity. Yes, it may be happening behind the scenes. People like [00:25:35 unintelligible] don’t require us to provide formulations. We sell ultrasonic equipment. Outside of that, we sell it without the nano stabilizer. Frequently, sometimes it goes with, something without, some people have their own, some people don’t but pharma generally always have their own. So if they buy our equipment than they do, sometimes We always know why it’s possible that they’re using it for that. It’s possible they using it for something else or for several things at once. If they bought the formulation from us, then we would know. But they don’t because they don’t have to. Because they know how to do this very well. 

Sonia Gomez: Yes. 

Dr. Alexey Peshkovsky: So we’re kind of in the dark. And we’re not asking, and we asked they couldn’t tell us. And so I don’t really know.

Sonia Gomez: I’m so nosy. I’d be like, Yes, what do you want this machine for?

Dr. Alexey Peshkovsky: Well, sometimes we ask, but sometimes it’s better not to ask. 

Sonia Gomez: Yes. Don’t Ask Don’t Tell policy. 

Dr. Alexey Peshkovsky: Yes. And generally, there is no discussion with them. They just get it, and it’s a purchasing person that just reaches out not to meet our people. And so a transaction is done, but generally, there’s not a lot of discussions. So I don’t really know about Big Pharma and getting into it. I know that small pharma is getting better for sure in getting formulations.

Sonia Gomez: Yes. 

Dr. Alexey Peshkovsky: But small pharma is really no different than many regular pharma, regular cannabis guys. It’s sophisticated farmer people are very– sophisticated cannabis space people are a very pharmaceutical company like because the word pharmaceutical company is generally kind of like negative words if you’re a cannabis person, but it doesn’t have to be. I mean, they’re not all [00:27:24 inaudible]

Sonia Gomez: Yes. No, I know. I agree.

Dr. Alexey Peshkovsky: So, small pharma is in it, and non-pharma people are definitely in it. Cannabis people and large pharma. They don’t really know.

Sonia Gomez: I would have to agree. I don’t think that it has to be a negative thing. I think it’s achieved a negative reputation, not because of what they do more so because of what the doctors– how the doctors are managing patients. I think that the doctors are going to pharmaceutical, the painkiller industry, for instance, has a terrible reputation. 

I think doctors are incentivized to go to pharmaceutical pain management as a first– It’s like the first reaction to somebody saying I’m in pain. They just want to give them a quick fix, not thinking about the ripple effect of that. And so I think that that’s where the negative stigma comes from. 

I myself am a victim of that, where I felt abandoned by my medical system, and certainly my doctors who were spending very little time with me trying to understand me as a patient. And we’re just layering medicine after medicine after medicine, and it was creating a terrible chemical reaction for me, and no one would listen or help me understand my alternatives. 

I love the work that you’re doing. I think it’s so super necessary, and I want to understand, like what facets of the business are you most in? Are you most intrigued by, or are you involved in right now? How does the company engage with you, I guess? Does a cannabis or CBD company, or is it the manufacturer that comes to you to license or purchase the technology for your delivery systems?

Dr. Alexey Peshkovsky: So, at this point, we don’t consider ourselves specifically a cannabis service company. Although most of what we do is for cannabis, we don’t actually work with cannabis ourselves. Not at this point. We provide the equipment and the formulations for people to do what they want to do. It turns out that a lot of that is cannabis. But it doesn’t have to be, and the equipment is the same. The formulations are also basically the same that nano stabilizer can work for any type of cannabis extract, but I can also work for other things—for vitamins for any oil compatible and non-water compatible bioactive. It works the same way. And there are many customers that use it for that. So generally people contact us through the website most of the time, or we’ll have several mechanisms by which people can contact us. And they make requests, or they ask questions, or they directly go for quotes. And we provide what they asked for, and we consult them sometimes. Sometimes we provide the full, complete turnkey solutions. Sometimes we provide a part of it if they have another part. So I guess that’s–

Sonia Gomez: It’s pretty multifaceted

Dr. Alexey Peshkovsky: Yes. Simultaneously, we constantly do research and development, including pharmacokinetic studies like right now we’re involved in pharmacokinetic studying on CBD, comparing nanoemulsions with alternative formulations and in different types of nanoemulsions delivery methods. So we try to stay ahead because once you develop a type of product or service, generally it’s successful for a while, and then you have to offer the next thing and the next thing. 

Also, it’s enjoyable. I’m trained as an academic scientist, I ended up doing business, but frankly, I feel much happier in the lab, in the electronics lab, in the chemical lab or biochemical lab. A lot happier than I am doing business and looking at the bank statements and things like that. So, we enjoy R&D, and we do a lot of it, and it actually pays for itself pretty, pretty well. So yes, that’s the story.

Sonia Gomez: I love that. What were some of the challenges when you started to serve the cannabis industry? Did you experience any challenges? Or are you safe from them because you’re serving more industries than just cannabis and hemp? Are you safe from the challenges that are associated with the industry? Or did you come up against some roadblocks or some things that you had to troubleshoot past in order to be involved here?

Some of the Challenges He Encountered When He Started to Serve the Cannabis Industry

Dr. Alexey Peshkovsky: By challenges, you mean banking problems and things like that? We didn’t see that because we don’t touch cannabis. We sell our systems to anyone if you happen to be a cannabis person, great if you’re not great, and if you don’t want to tell us maybe even better. So we didn’t see much about– The challenge, I guess switching from the pharmaceutical industry to the cannabis industry initially was that we were used to people understanding how to formulate because our customers were mainly pharma or similar to pharma, right? In the cannabis industry, people didn’t know how to do that and didn’t know why to do that. 

So initially, we tried to explain how to do this, then we started to provide some very basic formulations, and we have a pretty large blog portal with still a lot of information on from the early days on we keep adding information to it. Even that wasn’t enough. Our main idea was to sell our equipment like we always do, and the formulations were just something that people needed to know in order for them to want to buy our equipment. 

But then eventually, we figured out that we might as well just sell the formulations. Everybody was very happy when we started doing it because they don’t want to do it, they don’t want to figure it out. They are good at what they do, which are other things. And there’s no need to force them to pick up these new skills if they don’t want to do it. So don’t have time to do it or don’t have the ability to do it. So there was a technological, I guess, or an R&D challenge, which was great, because that’s what we’re like. And that was how to take this fairly complex formulation, which is a precise combination of many things. There are some carrier oils; there are some different emulsifier entities. There’s some [00:34:45 unintelligible], there’s a bunch of stuff that has to all happen correctly together for you to be able to make a nanoemulsion with our equipment or pretty much any kind of nanoemulsion that’s going to be a complex formula. So we made it all sort of in one.

It took a little while. I guess for about a year to develop a blend where all the components already there and to the user, it looks like one thing. It’s like a creamy, creamy substance that you can just add your extra to and add some water and sonicate them. And you’ll get [00:35:28 unintellible]. So to get that blend to be broad-spectrum in the sense that it can handle many different types of extracts, you don’t have to reformulate every time and to make it convenient, comfortable for people to use and to develop all the recipes for people to follow, that took some doing. And I guess that was an interesting challenge that resulted in a product that we’re very happy providing people are generally happy getting and so it’s a challenge that turned into a very good opportunity. 

Now, we’re on the other side of that. And there are always more challenges. For example, the next one that is very interesting and we’re essentially done with developing is making solid nanoemulsion. A solid nanoemulsion is no different from the liquid nanoemulsion except, instead of water, it’s in something that is very compatible with water, let’s say, a type of sugar derivative. But it’s solid at room temperature. So it’s still translucent, well-made nanoemulsion is translucent, they’re nearly transparent. And they become completely transparent when you add them to water, but its concentrated form, a good nanoemulsion is translucent. You can [00:36:49 unintelligible] it, right. So we can now make that into a solid, which means you can make a powder out of it. But you can also just leave it as a solid object like a lozenge, and it acts even quicker because it turns out that if you consume a liquid nanoemulsion sublingually, which many people try to do as a tincture, not an alcohol-based tincture, but a water-based tincture, right? Then it appears maybe to the user that they keep it under their tongue, but the reality is saliva actually washes it down. So it becomes a regular digestive absorption and not really sublingual, but sublingual absorption has its benefits. But to me, the solid lozenge is on your top right. So then you can benefit from nanoparticles, absorbed sublingually. You can also make a powder that was put into a beverage and will disappear, and there are many powders out there now, but if you put it into the water, it generally goes cloudy. It makes everything milky sometimes it precipitates down, sometimes it floats. So, that’s not what I’m talking about. I’m talking about a powder that will reconstitute into a clear solution like a product, right? So that is, I guess the newest thing that we’re pretty much ready to launch. We might even start selling directly. 

And then the next one that we’ve been very interested in developing, and something always distracts us from doing it. And so we’ve developed a concept over a year ago, and that works on a lab-scale, but to make a turnkey solution from it, is taking longer than I was expecting to take, but this was now again underway. It’s extraction into water. Currently, cannabis oils are extracted into solvents. Solvents could be originally hydrocarbons or ethanol, co2 and things like that, right? That will work very well. But if you could extract into water, wouldn’t that be nice, but it’s not flammable, it’s safe, it’s clean, it’s green, it’s cheap, it’s available locally. You could go into hemp farm, and instead of drying the hemp, now you don’t have to because it’s going to be in the water anyway. So you can just extract it directly, and you don’t have to take it the extraction facility. You can do it all locally, and you don’t have to worry about safety. 

So that would be nice, but we generally believe not to be possible. And I’m not talking about bubble hash. So you could break off trichomes into cold water. That’s different. That’s not extraction. That’s the hash. That’s making a trichome, it is making a hash [unintelligible] extract from later, but I’m talking about actual oil extraction. It’s generally not believed to be possible because oils don’t there’s all water in water, right? But the whole point of what we do is make oils behave as if they were soluble in water. Right? So with our technology, we can, therefore, extract in the water. 

There are some challenges, significant challenges associated with that.

Sonia Gomez: It’s science. It can’t be easy.

Dr. Alexey Peshkovsky: Yes, but it’s been already worked out on lab scale. So we’re able to do it in very small quantities. So nice question, scaling it up. But that’s exactly what our technology is built for them, in scaling things up. So I expect that to be the next big thing that we will launch hopefully in the New Year 2020.

Sonia Gomez: There’s a lot of buzz around water extraction right now. I think that there are people all over the place who are just through trial and error, trying to innovate the way that they’re doing things. It’s very, very exciting. I just returned from MJBizCon in Las Vegas. And as well as the Emerald Cup, which are two pretty contrasting representatives of where the industry is that the Emerald Cup is very much a representative of the old world cannabis industry that we knew pre-legalization and MJBizCon is certainly a landscape of the future of the industry, lots of science and technology that are represented there. Lots of things to be really excited about. Some things to be leery of. Definitely, the who’s who of know who to watch for as far as who’s growing and expanding there. So that’s really super exciting. I would love to hear from you knowing what you know now and having done the things that you have done and watching what you have watched, what would be some key pieces of advice, because I think there’s a lot of folks who are still standing on the perimeter trying to figure out how they integrate themselves their skill sets, perhaps their businesses into this space. And I’d love to hear from you. In this segment, I call words of wisdom, what would be some key pieces of advice, knowing what you know now that you could offer folks who were considering getting into this space? And the advice is meant to support them in accelerating their success here.

Key Pieces of Advice for People Considering Getting Into the Space

Dr. Alexey Peshkovsky: I guess I will have to come into the strongest scientific perspective. I guess that that would be my role in this. So currently, there are not too many regulations in the cannabis space, but that is going to change. And I think everybody understands that that’s going to change. And I think it’s good to be proactively compliant, even if you don’t yet really have to be.

It’s good. I think for those who are studying if they’re planning on surviving in this space for longer than it takes for all these regulations to kick in, which I’m thinking probably within the next year, or progressively more so right. So in order to survive after they keep him up, businesses will need to be compliant. And in order to be compliant, they need to be able to analyze what they’re doing, analyze what they have. In the water-compatible or water-soluble, as people call it space, it’s a very typical thing to not know how to analyze your product and not really worry about it, which creates significant problems in the THC space because then your product just doesn’t perform. But it’s largely under the radar in the CBD space because you can’t feel it. So you don’t really know that your stuff is not what is on the label. You could have a certain amount indicated on the label, but because the nanoemulsion separated—got stuck to the walls, sunk to the bottom or to the top, who knows what happened to it, oxidized is not there. Unless you analyze it, the user won’t know. And you might be able to start with your business and get going. And then the regulations come and start checking on what you have. And you might have to go out of business at that point, right. So I will say that sufficient education, self-education that allows one to be compliant with what is likely to come as far as regulations go is extremely important, and it’s good to start now because it takes a while to figure it out and to get this right. And I think it takes about the same amount of time as it will take the agencies to start regulating.

Sonia Gomez: I would have to say– I would have to agree 100%. I cannot emphasize enough the importance of future pacing the compliance and overdoing what others are underdoing. So I’ll just piggyback off of what you said for our words of wisdom today and share that how you do one thing is how you do everything and for me, there’s not enough emphasis on the data that supports your decision making. I think a lot of us are just working to survive. 

How you do one thing is how you do everything. - Sonia Gomez Click To Tweet

There’s a big difference between making decisions that allow you to survive versus making decisions that allow you to thrive in this landscape right now. And more often than not, we have to take responsibility ourselves for how we are empowering and educating ourselves with the information whether that’s through relationships or self-discovery, we really have to empower ourselves with the right information so that we can make educated decisions and how we are Operating right now as a self-governing industry. There is a lot of breadcrumbs on the trail right now, and they’re easy to follow if you’re willing to look, I think just so many folks are, are chasing the dollar right now and trying to get past the immediate pain point that they’re forgetting that these key intricacies are the things that make it possible for brands to stay to have that stickability.

There is a lot of breadcrumbs on the trail right now and they're easy to follow if you're willing to look. - Sonia Gomez Click To Tweet

So I will certainly piggyback and say that that is excellent advice. Whether you’re on the science level or if you’re working directly to the consumer from marketing data governs everything, and you can’t invest enough time or resources of money and team into collecting, analyzing and the leveraging your data to govern the way that you are making the decisions to grow and scale your company. 

There's a big difference between making decisions that allow you to survive versus making decisions that allow you to thrive in this landscape right now. - Sonia Gomez Click To Tweet

So those are our pieces of advice for you guys today. I’m so excited to talk and connect with you because I don’t think that we cover enough about the science and technology piece here and I think that we use a lot of buzzwords and marketing that don’t necessarily have a lot of meaning to the consumer who is looking for understanding on the how and the why these things are working. Alexey, if there are folks that want to reach out to you and are interested in you know, machinery or technology, or formulations or whatever you have to offer, where can they reach out to get connected?

Where to Them

Dr. Alexey Peshkovsky: The most straightforward thing to do is go on our website, and the website is sonomechanics.com. S-O-N-O and the word mechanics all together .com. Contact Us page, and there are different portals. You could ask for a consultation, request a quote, you can get more information and whatnot. And another more cannabis-related although on our website well, some cannabis exposure but there are many other things too. 

But we also have a blog portal, which you can also find on the website. It’s on top it says the blog. I think it’s blog.sonomechanics.com or something like that. But you can just get there through sonomechanics.com, and we have lots of articles there, information on cannabis. On things that we’ve worked on and general information and generally, you could read an article and then there’s a way to ask questions and talk to us, or switch from there into their contact us page on our website and contact us more directly with commercial requests. We love talking to people. We have lots of specialists here. Our people who know what they’re talking about and really love what they do. So By all means, we’ll be happy to talk to anyone.

Sonia Gomez: Amazing. Well, thank you so much for your time and attention today. It was enlightening to speak with you. I really enjoy hearing the science of this. My life was totally transformed by cannabis and hemp, and I was working with a holistic neurologist who had many products and research from Israel when he started to work with me. I only got to work with him for about three months and but the regimen that he laid out for me eliminated my dependency on medications, really empowered me as an individual and using microdosing, specific strains selection, a combination of cannabinoid-rich nutrients, and I’m super grateful that to this day I’m able to feel and function almost completely normally, minus the crazy that you get when you’re a mom, but other than that, I’m pretty good.

Dr. Alexey Peshkovsky: Four kids, I know what you’re talking about.

Sonia Gomez: I have four kids, too, and it is merciless. I’ll tell you. Oh. So yeah, just very grateful for the science and technology that is infiltrating the industry right now and how it’s helping us to understand the potential of these incredible plants. For those of you guys who are tuning in, thanks so much for being a part of this community. When you like and share content like this, you are a part of helping us move the needle towards legalization, ensuring that those of you who want and need safe access actually have it. 

It is our mission to empower you with all of the information and resources that you need to make these educated decisions about how you care for yourself, the people that you love, conditions that you may be suffering from or otherwise just take care of this beautiful gift of life that we get to enjoy if you’re someone looking for products that you can depend on to deliver the results that you’re looking for, check us out at medicalsecrets.com and if you’re a budding entrepreneur or Established brands looking to break through the glass ceilings and brick walls of this industry, check us out at theemeraldcircle.com, we are happy to help. 

Alexey, thank you again so much for your time and attention. 

Dr. Alexey Peshkovsky: Thank you very much.

Sonia Gomez: Guys. I’m your hostess with the most, Sonia Gomez, and this is The Hemp Revolution. We’ll see you on the next show, guys.

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