My name is James Brinkerhoff Jr. I’m super excited to be back and I have got a pretty cool topic of conversation today.
Will review an article from nature.com about The CB1 Receptor as an Important Mediator of Hedonic Reward Processing and will deep dive into why cannabis help people lose weight and enlighten people with a medical article from Nature journal that it’s not all about the munchies.
Enjoy and listen in.
I’m super excited about the future of terpenes and you’re going to be hearing a lot more about different terpene combinations and how people are getting amazing results. – James Brinkerhoff
Some Topics We Discussed Include:
00:29 – Why cannabis gives you the munchies
01:14 – Power of terpenes
01:38 – What makes us feel full? hunger and satiating
04:02 – THC and feeling hungry, losing weight
05:42 – The future of terpenes
People Mentioned / Resources
Connect with James Brinkerhoff
Connect with Sonia Gomez
James Brinkerhoff: Today I will be here with you. My name is James Brinkerhoff Jr. I’m super excited to be back and I have got a pretty cool topic of conversation today.
Why Cannabis Gives You the Munchies
Cannabis which means the munchies for many but it can also mean appetite suppression depending on the appropriate terpenes that are in the cannabis strain or added to the cannabinoids, or the product that you might be taking.
Cannabis which means the munchies for many but it can also mean appetite suppression depending on the appropriate terpenes that are in the cannabis strain.- James Brinkerhoff Click To Tweet
And while terpenes itself they do a good job for those who feel the munchies. Cannabis plus terpenes will actually supercharge it.
Okay. The olfactory researchers, the guys that are studying, or have been studying the sense of smell, the olfactory sense. They’ve always known about the incredible power of terpenes.
But few, few people really understood that terpenes are more powerful than many pharmacological compounds, including cannabinoids, even THC. And this has been demonstrated, I’m not just making this up. This has been demonstrated in articles and I’ll be posting an article down below from nature.com where they talk about this in this journal.
Power of Terpenes
On this issue, this highly respected journal nature, in this link, there’s a very interesting article that regards to the power of terpenes. This article contains some heavy psychopharmacology and neurochemistry. So not everyone’s gonna want to attack all the fine print but it’s evidence there.
So as to help those people let’s break it down a little bit. Right? The article points out that cannabis due to its ability to turn on the endocannabinoid receptors in the body especially these EC1 receptors in the brain. And that’s a known fact.
What Makes us Feel Full? Hunger and Satiating
And another well-known proven fact is that hunger and satiating, the feeling of feeling full is controlled primarily by the limbic system.
...the feeling of feeling full is controlled primarily by the limbic system. - James Brinkerhoff Click To Tweet
It’s kind of like our subconscious. And in the brain is called the hypothalamus. And a very general sense when the hypothalamus is excited, people get very very hungry due to the presence of receptors which causes hunger. Now when the ventral medial hypothalamus sitting next door right next to it is excited, satiated occurs that means you feel full. All right.
So when the ventral medial hypothalamus just next door to the hypothalamus gets stimulated or excited the hunger all disappears. Right? And this is due to the presence of receptors which cause us to feel full. Right?
So you take certain strains of cannabis especially through smoking or vaping. And it’s very interesting that happens as both the hypothalamus contains the EC receptors. When CB1 receptor grabs THC and certain groups of related terpenes, they cause profound hunger. Right? This is where we get the munchies. You know, smoke a joint, get the munchies. Right?
That’s what everybody’s used to. Or that’s what, kind of, the general populace talks about. Right? Or you see the pictures of the cartoons with a guy who just smoked it and now he’s eating tons of pizza and ice cream and stuff. Right?
THC and Feeling Hungry
Well, it’s interesting because the information contained in this article shows the general mechanism. Once THC gets injected directly to the lateral hypothalamus, you get hungry. Okay? If it gets directly into the ventral medial hypothalamus, there’s hunger. Okay? If there’s THC directed in the lateral hypothalamus with CB1 antagonist like this scent, the terpene, there’s hunger with an antagonist. And if you injected THC directly into the ventral medial hypothalamus with CB1 antagonist, that equals the feeling of being full.
So the study shows that the ventral medial hypothalamus will override the lateral hypothalamus when both are stimulated by THC and a CB1 receptor antagonist, terpene odor. So this THC blended with terpenes creates incredible results for many different things. Right? And a lot of people are stuck, I’m looking at a lot of these big corporate companies and I’m just kind of fed up with it but they’re all pushing this distilled, distilled THC and CBD. Which only does a fraction of the miracles that you hear about. The miracles with Rick Simpson’s oil, it’s a full-spectrum oil. Contains, that one even contains all the green matter. Right?
And it contains everything, all the terpenes, bioflavonoids. All the different cannabinoids that are in there. And that whole thing they’re all working together to create an effect. Right? Well, scientists now they’re tweaking these terpenes and these cannabinoids and they’re finding out amazing stuff. So here’s a product that you can lose weight with THC, THCV, and certain terpenes.
It’s pretty cool. You guys.
So let’s hear, what is true here for hunger and satiety is also true for pain modulation, mood effects, as well as most other known effects of cannabis. In other words, using the proper terpenes, we can turn on the endocannabinoid receptors. It’s like an activator in one area such as decreasing pain while blocking in another area such as decreasing hunger. Right?
So there’s all different, and there are probably thousands of different terpenes combinations that create different effects with this endocannabinoid. So are on the very beginning, the front, of a scientific movement to discover what all these cannabinoids can do for our endocannabinoid system and how us tweaking and testing all these terpenes how they can affect us. It could be a whole new wave of medicine. And I myself am super excited about this.
And I’m also talking to close friends of mine about the future of terpenes. And some of us are, last weekend I was in a meeting with a friend of mine, a product formulator, who was talking about how he thinks terpenes are the future. And we might find out about terpenes, we might not even need cannabis to effectively work on some of these maladies and ailments with just pure terpenes. It’s pretty exciting.
So with that being said you guys, I think that terpenes are generally the future and it’s a big area to study. So I may leave the link below to this article and I hope you guys got a lot of value out of this.
The Future Of Terpenes
I’m super excited about the future of terpenes and you’re going to be hearing a lot more about different terpene combinations and how people are getting amazing results. And science too.
And actually, we want to include the scientific evidence that this is working for people all around the world and the scientists that are studying this stuff. So if you ever thought that cannabis, all it could do is give you munchies and make you fat, I hope I just proved you wrong.
So if you ever thought that cannabis, all it could do is give you munchies and make you fat, I hope I just proved you wrong. -James Brinkerhoff Click To Tweet
The link to this Nature Journal Article is going to be below and I’m super excited for your comments below. Tell me what you think. And we can’t wait to see you on the next episode of On The Rise podcast. Peace out.
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