Most people have heard of a chemical called THC, which is the ingredient in marijuana that gets users high. But recently, attention has shifted to another compound in marijuana called CBD — and for good reason. Because while doctors can’t seem to look past certain side effects of THC, CBD doesn’t appear to present that problem. On the other hand, evidence of CBD’s medical benefits continues to grow. Below are the must-know facts about CBD oil that can change your mind.
CBD Is The Key Ingredient In Cannabis
CBD is one of over 60 compounds found in cannabis that belong to a class of molecules called cannabinoids. Of these compounds, CBD and THC are usually present in the highest concentrations, and are therefore the most recognized and studied. CBD and THC levels tend to vary among different plants. Marijuana grown for recreational purposes often contains more THC than CBD. However, by using selective breeding techniques, cannabis breeders have managed to create varieties with high levels of CBD and next to zero levels of THC. These strains are rare but have become more popular in recent years.
CBD Is Non-Psychoactive
Unlike THC, CBD does not cause a high. While this makes CBD a poor choice for recreational users, it gives the chemical a significant advantage as a medicine, since health professionals prefer treatments with minimal side effects. CBD is non-psychoactive because it does not act on the same pathways as THC. These pathways, called CB1 receptors, are highly concentrated in the brain and are responsible for the mind-altering effects of THC. A 2011 review published in Current Drug Safety concludes that CBD “does not interfere with several psychomotor and psychological functions.” The authors add that several studies suggest that CBD is “well tolerated and safe” even at high doses.
CBD Reduces The Negative Effects Of THC
CBD seems to offer natural protection against the marijuana high. Numerous studiessuggest that CBD acts to reduce the intoxicating effects of THC, such as memory impairment and paranoia. CBD also appears to counteract the sleep-inducing effects of THC, which may explain why some strains of cannabis are known to increase alertness. Both CBD and THC have been found to present no risk of lethal overdose. However, to reduce potential side effects, medical users may be better off using cannabis with higher levels of CBD.
CBD Is Still Illegal
Even though CBD shows much promise as a medicine, it remains illegal in many parts of the world. CBD is classified as a Schedule I drug in the United States and a Schedule II drugin Canada. On the other hand, the U.S. Food and Drug Administration recently approved a request to trial a pharmaceutical version of CBD in children with rare forms of epilepsy. The drug is made by GW Pharmaceuticals and is called Epidiolex. According to the company, the drug consists of “more than 98 percent CBD, trace quantities of some other cannabinoids, and zero THC.” GW Pharmaceuticals makes another cannabis-based drug called Sativex, which has been approved in over 24 countries for treating multiple sclerosis. A patent awarded to the U.S. Health and Human Services in 2003 (US6630507) also covers the use of CBD as a treatment for various neurodegenerative and inflammatory disorders.